suPhp

http://blog.sinjakli.co.uk/2009/05/27/wordpress-with-suphp/

apt-get install apache2 php5 mysql-server libapache2-mod-suphp

Having followed the WordPress installation guide you should have a working database (I sort of recommend phpmyadmin for this, especially if you want to do this in a GUI) and configuration. Now for the important part. You need to configure suPHP, and to be honest this is almost completely trivial.  First enable the module:

a2enmod suphp

Then edit the suphp config file at /etc/suphp/suphp.conf so that it contains either the line:

check_vhost_docroot=true

or the line:

docroot=/path/to/your/docroot/

The first will allow suPHP to run anywhere you define a DocumentRoot in your Apache vhost, the latter will allow you to point suPHP to a specified DocumentRoot.